Alpha GPC

AlphaGPC

Product Name: Alpha GPC

Other name: L-α-Glycerylphosphorylcholine (GPC),anhydrous 

CAS NO.:28319-77-9 

 Molecular formula: C8H20NO6P

Molecular weight: 257.2213 

L-Alpha glycerylphosphorylcholine (alpha-GPC, choline alfoscerate) is a natural choline compound found in the brain. It is also a parasympathomimetic acetylcholine precursor which may have potential for the treatment of Alzheimer's disease and other dementias.

Alpha-GPC rapidly delivers choline to the brain across the blood–brain barrier and is a biosynthetic precursor of acetylcholine.It is a non-prescription drug in most countries and in the United States it is classified as generally recognized as safe (GRAS).

Studies have investigated the efficacy of alpha-GPC for cognitive disorders including stroke and Alzheimer's disease. An Italian multicentre clinical trial on 2,044 patients suffering from recent stroke were supplied alpha-GPC in doses of 1,000 mg/day for 28 days and 400 mg three times per day for the five ensuing months. The trial confirmed the therapeutic role of alpha-GPC on the cognitive recovery of patients based on four measurement scales, three of which reached statistical significance.Commonly used doses are 300 to 1,200 mg daily.

Function: 

1. Increases human Growth Hormone (HGH)

Increases in endogenous human Growth Hormone (hGH) secretion by the anterior pituitary in conjunction with Growth Hormone Releasing Hormone (GHRH); that is, both Alpha-GPC and GHRH act concertedly to stimulate the release of hGH, naturally;

2. Improved Mental Focus and Stimulation of Cognitive Function

Stimulation of the enzymatic synthesis of phosphatidylcholine (PC) in nerves, muscle cells and all cell membranes, counteracting the age-related decrease in phospholipid (PC) biosynthesis; thus, Alpha-GPC contributes directly to improved mental focus and stimulation of cognitive function;

3. More Strength from work-outs and training programs

Acts as a precursor of acetylcholine (ACh); thus, Alpha-GPC activates cholinergic transmission which permits the development of more strength from work-outs and training programs, plus reducing levels of somatostatin in the hypothalamic-pituitary axis;

4. Improved lipotrophic functions in the liver

Elevations in blood and tissue levels of the essential nutrient, choline, which supports improved lipotrophic functions (methyl group transferases) in the liver. Research has shown that fatty liver, a condition associated with obesity, diabetes and heavy alcohol consumption, often leads to cirrhosis of the liver or liver failure. Studies conducted by Alan L. Buchman, M.D., associate professor of medicine at The Feinberg School of Medicine at Northwestern University, have shown that fatty liver can be prevented and possibly even eliminated with increased levels of choline. Alpha-GPC also acts synergistically with the body's store (and/or supplementation) of S-adenosyl-L-methionine (SAM or SAMe) and folic acid, vitamin B12 and vitamin B6 to facilitate methyl group transfers in the brain and liver;




Have questions about our products and services? 

Let us help. Call us at one of the numbers provided or send us an E-mail by click " Inquire Now"! 

Tel: +86-21-68453907

Cell/what's app/skype/dingtalk: +86-17717633275


HMB CA|Hordenine hydrochloride|Huperzine A|Daidzein



Specification for Alpha GPC: 

 

Test items

Specification

Description

White powder,

Neutral odor, very highly hygroscopic.

Identification(NMR)

Conforms to the standard

Solubility(H2O, 10% w/v)

Clear

Bulk Density (Untapped)

0.90g/cm3~1.08g/cm3

Stability

Dry and light protected storage;

Stable under normal usage.

Color of solution

≤Y7

Water content

≤2.0%

pH

7.5~9.0

Specific Rotation[α]25D

-2.4O~2.95O

Related Substances (HPLC)

G.P.E. :<0.2%

Glycerophosric acid: <0.2%

Related Substances(TLC)

Single spot

Purity(by Titration)

L-α-Glycerophosphoryl Choline

≥99.0%

Solvents Residue(Ethanols)

≤1.0%


label: Alpha GPC