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L-Ergothioneine
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L-Ergothioneine
L-Ergothioneine is a natural antioxidant that can have a protective effect on cells in the human body and is an important active substance in the organism, it has many physiological functions, such as, scavenging free radicals, detoxification, maintaining DNA biosynthesis, normal cell growth and cellular immunity.
ZNCBIO is a professional L-Ergothioneine China supplier and manufacturer, we have rich experience for exporting. Please be sure to email us at info@zncbio.com when you have any demands.
CAS No.: 497-30-3
TYPE: 99% Min
BRAND: ZNCBIO
MOQ: 1.0KGS
What is L-Ergothioneine?
L-Ergothioneine is a natural amino acid derivative with strong antioxidant properties. It is a sulfur-containing amino acid derivative with a thiol group in the molecule, which enables it to effectively neutralize free radicals in the body and reduce oxidative stress.
L-Ergothioneine is synthesized by certain microorganisms (such as fungi, bacteria, etc.) and is transmitted through the food chain, especially in mushrooms.



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Natural Sources of L-Ergothioneine
The natural sources of L-Ergothioneine mainly include the following foods and microorganisms:
1. Mushrooms
Mushrooms are one of the richest natural sources of L-Ergothioneine. Various types of mushrooms contain this substance, especially the following:
- Lentinula edodes
- White mushrooms (Agaricus bisporus)
- Boletus edulis
These mushrooms are much higher in L-Ergothioneine content than other foods, so they are an important source of L-Ergothioneine in the human diet.

2. Certain bacteria and fungi
L-Ergothioneine can also be synthesized by certain bacteria and fungi, especially Actinobacteria and other fungal species. These microorganisms exist in soil and other natural environments and provide L-Ergothioneine to plants and animals.
Actinomycetes, molds and fungi synthesize L-Ergothioneine in their metabolic processes, as important producers of this substance in the natural environment.
3. Some plants
Although the content of L-Ergothioneine in plants is relatively small, some plants can also provide a small amount of L-Ergothioneine. For example, some beans, grains and green leafy vegetables contain trace amounts of L-Ergothioneine.
4. Animals
Although animals contain L-Ergothioneine, their content is much lower than that of mushrooms. L-Ergothioneine is taken up through the animal food chain and accumulates in organs such as liver, kidneys, eyes and skin.
5. Other sources
In addition to the above main sources, some foods such as liver, kidneys and other visceral foods also contain small amounts of L-Ergothioneine, but their contribution to the daily diet is small.
Health Benefits of L-Ergothioneine
L-Ergothioneine has received increasing attention in recent years as a natural antioxidant. Studies have shown that it has a variety of potential health benefits, and here are some of the main health benefits:
1. Powerful Antioxidant Effect
L-Ergothioneine has powerful antioxidant properties that can neutralize free radicals in the body and reduce oxidative stress. Free radicals are an important factor in cell damage, aging, and a variety of chronic diseases (such as cancer, cardiovascular disease, diabetes, etc.).
Therefore, the antioxidant effect of L-Ergothioneine helps protect cells from oxidative damage.
2. Anti-cancer Potential
Some preliminary studies suggest that the antioxidant properties of L-Ergothioneine may help prevent cancer. By reducing oxidative damage, L-Ergothioneine may reduce the risk of cancer cell mutations, although more research is needed in this area to confirm its specific mechanism.
3. Liver and Kidney Protection
L-Ergothioneine is found in higher concentrations in the liver and kidneys, suggesting that it may play an important role in the protection of these two organs. Its antioxidant effects help reduce liver and kidney damage, especially in the face of damage caused by toxins or drugs.


4. Anti-aging Effect
Due to its antioxidant properties, L-Ergothioneine may have anti-aging effects. It protects the skin and other tissues from damage during the aging process by reducing oxidative stress. L-Ergothioneine helps maintain skin health and reduce the formation of fine lines and wrinkles. It is an important ingredient in some skin care products.
5. Promote Skin Health
The use of L-Ergothioneine in skin care is gradually gaining attention, especially in anti-aging and anti-inflammatory aspects. It helps reduce oxidative damage to the skin caused by factors such as UV rays and pollution, helps maintain skin barrier function, and reduces inflammatory responses, thereby keeping the skin healthy and youthful.
6. Improved Eye Health
Due to its antioxidant effects, L-Ergothioneine is considered beneficial for eye health. It may help slow the progression of eye diseases such as age-related macular degeneration (AMD) and maintain healthy vision by protecting the retina from oxidative damage.
7. Brain Health and Protection
L-Ergothioneine is found in higher concentrations in the brain and may be beneficial for cognitive function and the health of the nervous system. Studies have shown that it may help protect the brain from oxidative damage and delay the onset of Alzheimer’s and other neurodegenerative diseases. L-Ergothioneine supports brain cell health by reducing oxidative stress.
8. Cardiovascular Health
L-Ergothioneine may help protect the cardiovascular system and reduce the negative effects of oxidative damage on blood vessels and the heart. Some studies have shown that it helps prevent cardiovascular diseases such as hypertension and atherosclerosis by reducing inflammation and oxidative stress.
9. Anti-inflammatory Effects
L-Ergothioneine has anti-inflammatory effects and can help relieve a variety of health problems caused by inflammation. It is able to modulate inflammatory responses by reducing oxidative stress, which is particularly beneficial for people with chronic inflammatory diseases such as arthritis, metabolic syndrome, etc.

10. Strengthen the Immune System
L-Ergothioneine may enhance the function of the immune system through its antioxidant properties. It can help regulate immune responses and enhance the body’s ability to fight infection and disease.
L-Ergothioneine shows promise in multiple areas of health through its powerful antioxidant, anti-inflammatory, and immune-boosting effects. Not only does it benefit skin, brain, and cardiovascular health, it may also support anti-aging, anti-cancer, and eye health. Although research on L-Ergothioneine is still ongoing, it is undoubtedly a natural substance with multiple health benefits.
Commercial Applications of L-Ergothioneine
L-Ergothioneine is widely used in the following categories of products due to its antioxidant, anti-aging and anti-inflammatory properties:
1. Dietary supplements
- Antioxidant supplements: As a natural antioxidant, L-Ergothioneine is often used in antioxidant health supplements to help slow the aging process and protect cells from free radical damage.
- Immune boosting supplements: L-Ergothioneine helps boost immune system function and is therefore also commonly found in immune support supplements.
- Skin health supplements: Used to promote skin health, reduce oxidative stress, and slow the aging process.
- Neuroprotective products: Due to its protective effects on the brain, L-Ergothioneine may also be used in neuroprotective drugs and health products to help slow the progression of neurodegenerative diseases such as Alzheimer’s disease.


2. Skin care products
- Anti-aging skin care products: L-Ergothioneine is used in anti-aging skin care products to help reduce fine lines and wrinkles and keep the skin youthful.
- Antioxidant creams: Its antioxidant properties can help reduce damage to the skin caused by external environments such as UV rays and pollution, and is often used in daily care products.
- Moisturizing products: Because L-Ergothioneine has the effect of improving the skin barrier function, it is also used in moisturizers and serums to help maintain the skin’s moisture balance.
- Anti-inflammatory and sensitive care: It can help relieve skin problems caused by inflammation and is suitable for care products for sensitive skin.
- Eye cream and eye serum: The antioxidant and protective effects of L-Ergothioneine make it an ideal ingredient in eye care products, helping to relieve eye fatigue and reduce eye problems caused by oxidative damage, such as dark circles and eye bags.
3. Shampoo and hair care products
- Antioxidant shampoo and conditioner: L-Ergothioneine helps protect hair from environmental damage, promotes healthy hair growth, and reduces hair problems caused by oxidative damage.
- Anti-aging hair care products: By protecting the cells of the scalp and hair, delaying the aging process, it helps keep the hair shiny and strong.


4. Functional foods
- Anti-aging drinks and foods: L-Ergothioneine can be added to functional drinks, nutrition bars, healthy snacks and other foods as a natural anti-aging and antioxidant ingredient.
- Probiotic foods: Due to its immune-enhancing properties, L-Ergothioneine can also be used as an ingredient in probiotic foods.
- Sports recovery supplements: L-Ergothioneine’s antioxidant properties help reduce muscle fatigue after exercise and promote recovery, so it is also used in sports nutrition supplements.
L-Ergothioneine can be widely used in dietary supplements, skin care products, shampoos, eye care, functional foods, sports nutrition and other fields. Its antioxidant, anti-aging, anti-inflammatory and immune-enhancing properties make it an ideal ingredient in a variety of health and beauty products.
If you want to know more about the product applications, advantages, prices and other information of L-Ergothioneine, please contact us or leave a message.
Why choose ZNCBIO L-Ergothioneine?
As a supplier of ZNCBIO, the main reasons for choosing ZNCBIO L-Ergothioneine include:
1. High quality assurance
ZNCBIO L-ergothioneine undergoes strict quality control and testing to ensure high purity and stability, meeting customers’ demand for high-quality products.
2. Reliable supply
ZNCBIO has stable production capacity and reliable supply chain to ensure timely delivery and avoid affecting customers’ business due to out-of-stock.
3. Global certification
The company’s products meet international quality standards, have license certification, and are suitable for export to various markets, helping traders expand their global business.
4. Competitive pricing
ZNCBIO offers market-competitive prices to help traders increase profit margins, meet customer needs and optimize costs.
Choosing ZNCBIO L-ergothioneine as a product allows traders to obtain first-class product quality, reliable supply and strong market support, thereby winning more customers and business opportunities.
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