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TAURINE
Semaglutide
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used primarily for the treatment of type 2 diabetes and obesity. It is an important sports nutrition ingredient. ZNCBIO is a professional Semaglutide China supplier and manufacturer, we have rich experience for exporting. Please be sure to email us at info@zncbio.com when you have any demands.
CAS No.: 910463-68-2
TYPE: JP GRADE & USP GRADE
BRAND: ZNCBIO
MOQ: 1.0 G
Introduction Of Semaglutide
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used primarily for the treatment of type 2 diabetes and obesity. It is a synthetic analog of human GLP-1 with improved pharmacokinetic properties, enhancing its efficacy and half-life.
Basic Information
Molecular Formula: C187H291N45O59
Molecular Weight: ~4113.58 g/mol
Appearance: White or off-white crystalline powder
Purity: ≥98% (HPLC detection)
Packing specifications: 1mg, 5mg, 10mg, 50mg, etc. (can be customized according to customer needs)
Storage conditions: Long-term storage from -20°C to -80°C, short-term storage from 2-8°C
Physical Properties
Solubility: It can be dissolved in water or buffer solution (such as PBS), but its solubility in water is low, and it usually requires pH adjustment or the use of co-solvents.
Stability: It is stable under dry and low temperature conditions, but is sensitive to light, heat and humidity.
Function of Semaglutide
Semaglutide is a GLP-1 receptor agonist with multiple beneficial effects on metabolism and overall health. Its primary functions include:
1. Blood Sugar Control (Antidiabetic Effect)
- Stimulates insulin secretion in response to high blood glucose levels.
- Suppresses glucagon release, reducing excess glucose production by the liver.
- Slows gastric emptying, preventing rapid spikes in blood sugar.
2. Weight Loss & Appetite Suppression
- Reduces hunger by acting on appetite-regulating centers in the brain.
Promotes satiety and decreases calorie intake. - Helps in weight loss, making it useful for obese and overweight individuals.
3. Cardiovascular Benefits
- Lowers the risk of heart disease by reducing blood pressure and cholesterol levels.
- Improves blood vessel function and reduces inflammation.
- May reduce the likelihood of heart attacks and strokes in high-risk patients.
4. Potential Neuroprotective Effects
- May have benefits in treating neurodegenerative diseases like Alzheimer’s and Parkinson’s.
- Enhances brain function and reduces inflammation in nervous system disorders.
5. Other Potential Benefits
- Could improve liver health, reducing the risk of non-alcoholic fatty liver disease (NAFLD).
- May help in managing polycystic ovary syndrome (PCOS) by improving insulin sensitivity.
Application of Semaglutide
Semaglutide raw powder is primarily used in the following products:
1. Pharmaceutical Products
Diabetes Medications (Type 2 Diabetes Treatment)
- Examples: Ozempic® (Injectable), Rybelsus® (Oral Tablets)
- Used to lower blood sugar levels and improve insulin sensitivity.
Anti-Obesity Medications (Weight Management Drugs)
- Example: Wegovy® (Injectable)
- Approved for chronic weight management in obese and overweight individuals.
2. Injectable & Formulation Products
Subcutaneous Injection Solutions
- Semaglutide is often formulated as a sterile lyophilized powder that requires reconstitution before use.
Oral Tablets (Advanced Drug Delivery Systems)
- Example: Rybelsus®, which uses SNAC (sodium N-[8-(2-hydroxybenzoyl) amino] caprylate) technology for oral absorption.
3. Research & Development (R&D and Clinical Trials)
- Neuroprotection: Potential applications in Alzheimer’s and Parkinson’s disease.
- Cardiovascular Health: Studied for reducing cardiovascular risks in diabetic and obese patients.
- Liver Health (NAFLD/NASH Treatment): Investigated for non-alcoholic fatty liver disease management.
Semaglutide is primarily prescribed for diabetes and weight management, but it also has potential in the nutraceutical, metabolic management, cardiovascular and neuroprotective fields. Please ask us if you would like to learn more.
Contact Details
SHANGHAI ZNCBIO
Key Considerations for Factories Using Semaglutide
Factories handling Semaglutide raw powder must ensure quality, safety, and regulatory compliance. Key considerations include:
1. Regulatory Compliance
Follow GMP, FDA, EMA, ISO standards and ensure proper drug registration (DMF).
2. Quality Control
Maintain ≥99.5% purity, conduct HPLC & microbial testing, and ensure batch consistency.
3. Manufacturing Process
Implement high-precision synthesis, lyophilization, and sterile processing for injectable formulations.
4. Storage and Handling
Store at -20°C, protect from light & moisture, and use cold chain logistics for transport.
5. Supply Chain Management
Source from reliable API suppliers, ensure raw material traceability, and comply with import/export regulations.
6. Safety Measures
Train workers, use PPE, follow hazardous material protocols, and ensure environmental compliance.
Factories must focus on compliance, quality assurance, safety, and supply chain integrity to produce high quality and legally approved Semaglutide products.
More Product Recommendations
Shanghai ZNC Biotechnology Co., Ltd.(ZNCBIO) is a supplier of various chemicals and packaging materials. In addition to Semaglutide , it can also provide you with products in many fields such as nutritional supplements, food additives, APIs, cosmetics and minerals.
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